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Both laboratory-based assays and point-of-care tests that provide results for HSV-2 antibodies from capillary blood or serum during a clinic visit are available.
Most persons infected with HSV-2 have not had the condition diagnosed.
Many such persons have mild or unrecognized infections but shed virus intermittently in the anogenital area.
As a result, most genital herpes infections are transmitted by persons unaware that they have the infection or who are asymptomatic when transmission occurs.
Management of genital HSV should address the chronic nature of the disease rather than focusing solely on treatment of acute episodes of genital lesions.